Purpose - Evaluation of hydrogen-powered short/medium- and long-range passenger aircraft with respect to the locations of their liquid hydrogen (LH2) tanks. Possible tank layouts are: one tank aft and one tank behind the cockpit versus two tanks aft. Two tanks aft result in larger travel of the aircraft's center of gravity (CG) while the fuel is consumed during the flight. --- Methodology - A special purpose Excel tool takes up those elements from conceptual aircraft design with an influence of the tank layout on the aircraft's fuel consumption. These elements are horizontal tail sizing and fuselage extension; tail, tank and bulkhead mass estimation including mass growth factors; as well as zero-lift and induced drag estimation. The methodology is kept generic. Where necessary, Airbus A320 parameters have been used and scaled as required. --- Findings - A configuration with two tanks at the rear of the aircraft is best for short- and medium-range aircraft (harmonic range: 2100 NM), requiring 0.17% less fuel consumption compared to a layout with one tank aft and one tank behind the cockpit. The opposite, a configuration with one tank aft and one tank behind the cockpit is best for long range aircraft (harmonic range: 6200 NM), requiring 0.66% less fuel consumption compared to a layout with two tanks at the rear of the aircraft. --- Research Limitations - Important elements related to the question have been calculated with precision based on conceptual aircraft design. These selected elements, however, do not cover a full and iterative aircraft design calculation. Instead, mass growth factors have been used to convert a local mass increase (i.e., from an increased horizontal tail) to a global mass increase on aircraft level due to aircraft resizing. --- Practical Implications - Pros and cons of two LH2 tank layouts have been determined for given aircraft parameters. The Excel tool can easily be adapted to other parameters or tank layouts. --- Social Implications - The thesis provides an answer to one of the many questions related to the design of hydrogen passenger aircraft. As such, it has brought these environmentally superior LH2 aircraft closer to reality. --- Originality - Apparently, the two most discussed fuselage mounted LH2 tank layouts for passenger aircraft have been evaluated on aeronautical fundamentals in public for the first time.